I have tried every type of formula there is to try, but nothing worked for my son. He was sick with a colic for the first four weeks of his life because of the formula. I tried Enfamil Nutramigen, and it worked. It is the only fromula that he can tollerate. The only problem with it is it's cost. And, we compared labels on Enfamil Prosobee, and Enfamil Nutramigen, and they are practaclly the same.