My derm prescribed differin gel for me about a year ago and at first it really worked but, unfortunately it dried out my skin and irritated the hell out of it. It caused my skin to become VERY red. Next, he switched me to the cream version, which in the beginning was much gentler on my skin than the gel. But, unfortunately it began to irritate my skin and I started developing cystic acne :( I am now on retin a micro which some how isn't nearly as irritating as differin. My skin still isn't perfect but, it is getting better. No major breakouts on retin a micro (been on it for 3 months now) :D Wouldn't recommend differin if you have sensitive/acne prone skin like me.