As you view the actual document and signatures, his stands out as he signed his name with a cursive flair, larger than any of the other signers, in true courageous defiance. He later said he signed in such a way that King George might be able to read his name without needing his reading glasses. His story lives on today when someone asks you to sign something and says, put your 'John Hancock' right here. UPDATE: I just found the quote: "There! His Majesty can now read my name without glasses. And he can double the reward on my head!"
-- John Hancock (upon signing the Declaration of Independence,
4 July 1776)