this is the best formula for my 5 week old daughter. It took three different formulas to find the correct one. She was always fussing, pulling her legs up to her chest, grimacing and making fists all the time. we noticed a change in about 48 hours and now when we put her in her swing or crib, she doesn't fuss at all, not even if she stays awake. She's more relaxed and smiling now too. Well worth the price. -Heather