I took buspar with an antidepressant of one kind or another for four years. I was then able to completly remove myself from psycotropic medications for two years until my Severe Anxiety Disorder and Panic Attacks came back recently. Once again, I find myself at peace with BuSpar. This stuff really works and is very well targeted. I like the fact that within 15-45 minutes after ingestion I begin to physically and mentally feel it's effect. (Tingling, pins and needles throughout the body, followed by an amazing sense of calm, an almost nirvana-like state of being.) I recommend this to anyone suffering with anxiety, but be warned...My mistake was to depend ONLY on BuSpar and other medications. That is why my symptoms returned. Now I practice meditation, eat healthy, avoid caffiene, and speak to a therapist.