Good when they work, but of all the different mail sites I've used they are the only one to go down for several days without any explanation. I'm primarily on hotmail and yahoo as well as a school account in addition to mail.com and not one of those others ever goes down for more than a day, most only go down for a few hours.
Mail.com has gone down half a dozen times in the several years I've used them, usually once a year for a few days. It may have gone out longer but when it won't come up for 2-3 days I don't bother checking it for a while.
This recent outage means I'll keep it only as a backup, I recently used it to list craigslist stuff so I wouldn't get spammed more on a primary account and now I'm possibly losing buyers.