I took Oxytetracycline for many years (around 7 years) and like others, I found it worked well on the acne but caused indigestion since it must be taken on a an empty stomach. I found if it is not taken correctly (ie everyday at the same time and on an empty stomach) my acne would strike back within a couple of days. I also found that taking this drug within a couple of hours of going to bed caused stomach pain during the night and eventually I had to stop taking this drug due to stomach problems caused by the long term use. I found the best and most effective times to take it was at 09:30 and 16:00. I'm now trying Isotretinoil - see http://www.acne.homestead.com for my user diary.
