I have had persistent mild/moderate acne for four years, I finally saw a derm and was prescribed three meds, one of them was plexion TS(sodium sulfacetamide), the other two were differin and minocycline. The S.S. smells terrible, I mean, it's sulphur! Its also gritty, which is useful in exfoliating dead skin and letting in penetrate further into the skin. It's primarily a topical anti-bacterial, meaning it kills the bacteria in the acne. I really dont like they way it feels or smells, but it's pretty damned strong, so functionality-wise, it's pretty good. I think it works better at preventing pimples than treating existing ones, although it does speed up the death of zits.
