I think Secretary of State will be the pinnacle of Hillary's career. She will not unseat Barrack Obama in 2012, and she will be viewed as too old when 2016 comes around. She has a better chance of becoming President if Obama, Biden, Pelosi, and Byrd all perished in a tragic gasoline fight accident.

She'll have to wait until 2016 to run, by then she'll be 68 years old. All will depend on whether or not she's in public life. I suspect she'll resign after Obama's first term to focus on making another run. She wants the Presidency; whether or not she'll get will depend on a lot of factors. Lots of Democrats will be waiting in the wings to make a run--they have a deep bench of candidates at this point and many will run in 2016.

Obama will most likely be re-nominated in 2012, no matter how weak politically he might be.

AS Imorovan says, not even a chance now ~ not that she had much to begin with!  America is not ready for a female President!  I can say this because, first off, I am a woman and secondly ~ women are emotional by nature, and in this time and age, that wouldn't be a good call. I am ready ~ funny button away!

LOL, she's not even a candidate anymore. Unless of course, she heads a successful "coup d'etat" :)