FeedDemon 5

Been using FeedDemon for several years and it gets better and better.
Originally developed by Nick Bradbury he latter sold his company to NewsGator and works for them further enhancing FeedDemon. It can display RSS feeds in multiple ways and you can set-up searches across RSS feeds. You can also download podcasts.
I have a NewsGator subscription that lets me synchronise RSS feeds on different computers, so if I read a feed at work it shows up read at home.
A really great piece of software.